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Fordyce Spots on Lips: What Are They and How Are They Treated?

In the realm of skincare and cosmetic medicine, patients often seek advice about small, pale bumps that can appear on their lips or elsewhere in the mouth. These are frequently Fordyce spots—a benign but sometimes distressing skin concern. Understanding what Fordyce spots are, why they appear, and what options are available for those bothered by their presence is key for clinicians and clients alike.

Fordyce Spots on Lips

What Are Fordyce Spots?

Fordyce spots are small, raised, pale or white-yellow bumps that occur on the vermilion border of the lips (the line between the colored part of the lips and the surrounding skin), inside the lips, or the genital area. They are:

  • Ectopic sebaceous (oil) glands: Fordyce spots are sebaceous glands that are present in locations where they typically wouldn’t be found, without association with hair follicles. On the lips, these glands normally produce sebum (oil) to help lubricate the skin.
  • Harmless and non-infectious: Fordyce spots are not contagious, not caused by infection or disease, and are not considered a health threat.
  • Common: Studies indicate that up to 80% of adults have Fordyce spots somewhere on their bodies; they’re particularly common on the lips as people age.
  • Appearance: They look like tiny white, yellow, or sometimes flesh-colored dots, rarely more than 2–3 mm in size, and typically cause no pain or itching.

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Why Do Fordyce Spots Occur?

Fordyce spots are considered a normal anatomical variation rather than a medical disorder. They are present from birth but typically become more visible during puberty, likely due to hormonal changes (especially androgens) that stimulate sebaceous glands. Their prominence can be influenced by:

  • Genetics: Some people are genetically predisposed to have more visible Fordyce spots.
  • Hormones: They often become more noticeable during periods of hormonal fluctuation.

They are not related to poor hygiene, sexually transmitted infections, or cancer.

Fordyce Spots Treatment

Because Fordyce spots are benign, treatment is usually not medically necessary. Most dermatologists and medical professionals recommend leaving them alone, especially since they often become less noticeable over time due to natural skin changes. However, some people seek treatment for cosmetic reasons, particularly if the spots cause distress or self-consciousness.

Commonly Considered Treatment Options: Fordyce Spots

1. Topical Treatments
  • Retinoids: Prescription-strength retinoid creams (such as tretinoin) may reduce the prominence of Fordyce spots with regular use. These must be used with caution, as they may cause irritation or sensitivity, especially on the lips.
2.Laser Therapy
  • CO2 Laser or Pulsed Dye Laser: These can ablate (remove) superficial skin layers and diminish the appearance of Fordyce spots. Risks include temporary discomfort, swelling, pigmentation changes, and (rarely) scarring.
  • Erbium-YAG Laser: Another laser option with high precision and minimal downtime.

3.Micro-Punch Surgery

  • Tiny tools are used to physically remove individual spots. This method is precise but can only treat a limited number of spots at a time and is rarely chosen for extensive Fordyce spots.
4. Electrosurgery or Radiofrequency
  • Used occasionally to destroy or shrink sebaceous glands. May be considered for persistent cases, though risks include minor scarring or pigment changes.
Note for Clinics: As Fordyce spots are entirely benign, informed consent and clear expectations are crucial, especially since some treatments may have side effects or only provide partial improvement.

How to Get Rid of Fordyce Spots?

While there’s no guaranteed or universally effective method to completely and permanently remove Fordyce spots, patients seeking improvement can consider the following approach:

Stepwise Guidance for Patients
  • Reassure and Educate:
  • Fordyce spots are normal, harmless, and not contagious. They do not need treatment for health reasons.
  • Cosmetic Treatment (If Desired): Topical retinoids under supervision for several weeks/months.
  • Laser therapy or other minor procedures by an experienced dermatologist.
  • General Skincare: Use gentle, non-irritating lip balms and cleansers. Avoid picking or squeezing the spots, which can cause inflammation or scarring.
  • Medical Consultation: Rule out other, similar-appearing conditions if spots have an unusual look, are painful, or accompany other symptoms.
  • Never self-diagnose; consult a dermatologist for persistent concerns.
What Doesn’t Work
  • Over-the-counter “spot” or acne treatments (like benzoyl peroxide) are not effective for Fordyce spots and may irritate the lips.
  • Home remedies (such as lemon juice, oils, or toothpaste) are not evidence-based and can cause skin irritation or damage.

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Conclusion

Fordyce spots on the lips are a common and harmless anatomical occurrence. While no treatment is medically necessary, there are some options available for those who are bothered by their appearance—including topical retinoids and various laser therapies. It’s important that patients and providers recognize Fordyce spots as benign and approach any cosmetic treatment with realistic expectations.

For aesthetic clinics and practitioners, providing clear education and reassurance is a cornerstone of quality patient care. Understanding Fordyce spots ensures appropriate guidance and empowers clients to make informed choices about their skin health.

Disclaimer: The information provided here is for general knowledge only and should not be considered medical advice. For any questions or concerns about your health or medications, please consult your physician or healthcare provider. They are best equipped to provide guidance specific to your medical needs.

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