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Medicare's GLP-1 Price Cuts: What Providers Need to Know

Recent headlines about Medicare GLP-1 price cuts for medications like Ozempic and Wegovy have generated significant patient interest and questions in weight loss practices across the country. As providers, understanding the details behind these announcements is essential for accurate patient counseling and managing expectations.

Medicare's GLP-1 Price Cuts: What Providers Need to Know

Two distinct federal initiatives are driving these changes: the Inflation Reduction Act’s drug price negotiation program (effective January 2027) and a voluntary manufacturer pilot program (starting mid-2026). 

Each has different implications for patient access and cost. Confusing the two can lead to disappointed patients and administrative headaches for your practice.

At IAPAM, we continue to follow developments in GLP-1 weight loss training and education, helping physicians navigate the rapidly evolving landscape of obesity medicine and understand the complex reimbursement policies that affect their practices.

In this article, you will learn:

  • The difference between the 2026 pilot program and 2027 price negotiation and which patients qualify for each
  • Why Medicare’s GLP-1 price cuts don’t automatically mean coverage for weight loss patients
  • Specific eligibility criteria and documentation requirements to help your patients access these programs
  • Practice management strategies to proactively screen patients and manage expectations

Table of Contents

The 2027 Price Reduction Under the Inflation Reduction Act

According to reporting by NBC News on November 25, 2025, the Centers for Medicare & Medicaid Services announced negotiated prices for 15 high-cost drugs under the Inflation Reduction Act’s drug price negotiation program. Among these medications are Ozempic®, Wegovy®, and Rybelsus®—all GLP-1 agonists manufactured by Novo Nordisk.

Key pricing details:

  • Standard dose: $274/month (down from $959 list price)
  • Higher-dose Wegovy: $385/month
  • Price reduction: 71%
  • Effective date: January 1, 2027

What This Price Actually Represents

It is critical to understand what this negotiated price represents. As explained in the Kaiser Family Foundation’s (KFF) analysis published on November 26, 2025, this $274 figure is the price Medicare will pay to manufacturers, not the patient copay.

Patient out-of-pocket costs will vary based on their specific Part D plan structure, deductibles, and whether they have reached catastrophic coverage. 

The negotiated price affects the plan’s cost basis, which may reduce patient copays, but does not guarantee a specific out-of-pocket amount for individual patients.

Projected savings (according to CMS data reported by NBC News):

  • Taxpayer savings: $12 billion
  • Medicare enrollee out-of-pocket savings: $685 million in 2027

Reuters reported on November 25 that the 2027 savings of 36% on net spending represents an improvement over the first round of Medicare drug price negotiations, which achieved 22% savings according to Goldman Sachs estimates.

Who Benefits from the 2027 Price Reduction

This price reduction applies to patients already receiving these medications for Medicare-covered indications. Currently, Medicare Part D covers GLP-1 agonists when prescribed for:
  • Type 2 diabetes
  • Cardiovascular disease in overweight or obese adults
  • Chronic kidney disease
  • Metabolic-associated steatohepatitis (MASH)
Patients receiving these medications for these covered conditions will benefit from the lower negotiated price starting in 2027.

Medicare Coverage Policy for Anti-Obesity Medications

The 2027 price reduction does not modify the fundamental coverage restrictions that have been in place for over two decades.

As detailed in AARP’s coverage guide updated on November 21, 2025, the Medicare Prescription Drug, Improvement, and Modernization Act of 2003 explicitly prohibits Medicare Part D plans from covering medications prescribed primarily for weight loss as part of the standard benefit. 

This restriction was implemented following concerns about diet medications in the late 1990s, including the fen-phen scandal.

Juliette Cubanski, deputy director of the program on Medicare policy for KFF, explained in the organization’s analysis that “there was skepticism of weight loss medications that existed at the time, and a sense that obesity was more of a behavioral problem than a medical condition.”

The bottom line: Patients seeking GLP-1 medications solely for weight management without qualifying comorbidities will not have coverage under the 2027 price negotiation program, regardless of how low the negotiated price becomes.

Current Coverage Parameters

Medicare Part D currently covers GLP-1 agonists only when prescribed for FDA-approved indications other than obesity alone.

The FDA approved Wegovy® for cardiovascular risk reduction in adults with established cardiovascular disease who are also overweight in March 2024, which opened the door for Medicare coverage in that specific population. Similarly, Wegovy®’s approval for MASH in August 2025 created another covered indication.

However, obesity as a standalone diagnosis remains excluded from standard Medicare Part D coverage.

The 2026 Manufacturer Pilot Program

On November 6, 2025, President Trump announced agreements with pharmaceutical manufacturers Eli Lilly and Novo Nordisk to dramatically reduce GLP-1 prices and expand Medicare coverage for obesity. According to the White House fact sheet released that day, this represents “the most significant actions ever taken by our Federal government to lower prescription drug prices.”

The agreements establish a voluntary pilot program that will begin in mid-2026, representing the first time Medicare will cover GLP-1 medications specifically for obesity, though only for patients meeting defined comorbidity criteria.

Pilot Program Pricing Structure

According to the White House fact sheet, under this pilot program:
  • Patient copay: $50/month (after deductibles)
  • Government payment to manufacturers: $245
  • Total cost: $295/month
  • Launch timeline: Mid-2026

The White House stated that “the Medicare prices of Ozempic, Wegovy, Mounjaro, and Zepbound will be $245, less than half the prices proposed by the Biden Administration on such drugs. State Medicaid programs will also have access to these medications at these prices.”

CNBC reported on November 6, 2025, that “Medicare will start covering obesity drugs for some patients for the first time starting mid-2026, a long-awaited move that could broaden the market for the medicines and spur more private insurers to cover them.”

Eligibility Criteria

According to CNBC’s reporting, which cited senior administration officials during a briefing on November 6, around 10% of Medicare beneficiaries will be eligible to receive GLP-1s for obesity and cardiovascular and metabolic benefits. Eligible patients will fall into three cohorts:
  • BMI ≥27: Plus prediabetes or history of cardiovascular disease
  • BMI >30: Plus heart failure with preserved ejection fraction, uncontrolled hypertension, or chronic kidney disease
  • BMI ≥35: No additional conditions required

A senior administration official explained the rationale to CNBC: “We are constraining the access for patients that will benefit clinically from it, we’ve worked very hard to strike a balance between broad access that just makes sure to capture patients that will benefit clinically.”

Documentation of these qualifying conditions will be essential for coverage approval. According to Eli Lilly’s press release on November 6, 2025, “starting as early as April 1, 2026, Medicare beneficiaries will pay no more than $50 per month for Zepbound (tirzepatide).”

Practice Management Implications

Preparing your practice for these changes requires proactive planning and clear communication strategies.

1. Proactive Patient Screening

Review your Medicare patient population to identify those who may qualify for the 2026 pilot program. Focus on patients with:
  • Documented obesity (BMI ≥27)
  • Uncontrolled hypertension
  • Heart failure with preserved ejection fraction
  • Prediabetes
  • Established cardiovascular disease
  • Chronic kidney disease
This proactive approach allows you to prepare patients for the mid-2026 launch rather than reacting to inquiries after the program begins.

2. Documentation Best Practices

Ensure accurate and comprehensive documentation of:
  • BMI measurements
  • Comorbid diagnoses
  • Blood pressure readings (for uncontrolled hypertension)
  • Diagnostic codes for heart failure or cardiovascular disease
  • Lab values indicating prediabetes
  • Kidney function tests showing chronic kidney disease
  • Treatment rationale and clinical necessity
This documentation will support prior authorization requests and coverage determinations.

3. Patient Communication Strategy

When patients inquire about the “Medicare price cuts” they have seen in the news, clarify:
  • Which program applies to their specific situation
  • Whether they have coverage for their intended indication
  • Expected out-of-pocket costs based on their Part D plan and eligibility status
  • Timeline for when changes take effect
Setting accurate expectations at the outset prevents disappointment and reduces administrative burden from appeals or grievances.

4. Stay Informed on Policy Evolution

Monitor updates from CMS as implementation details for both programs may be refined as launch dates approach.

The Kaiser Family Foundation noted in their analysis that a third round of Medicare drug price negotiations is expected to begin in February 2026, with 15 additional drugs to be selected. 

Policy in this area continues to evolve, and staying current with authoritative sources such as KFF, AARP, and CMS will help you provide accurate guidance to patients.

Expert Perspectives

Stacie Dusetzina, a health policy professor at Vanderbilt University, noted in NBC News’ coverage: “The price negotiations look very reasonable to me. It should hopefully provide some relief for taxpayers and beneficiaries in the long run.”

However, she also pointed out that the $274 negotiated price is higher than the $245 government payment in the pilot program, highlighting the complexity patients and providers must navigate.

Sean Sullivan, a professor of pharmacy at the University of Washington, observed in Reuters’ reporting that the Medicare negotiated prices may have broader market implications: “These prices are going to come down below the existing net prices. 

There will be some real savings. All of the other payers can see them. What is going to stop them from asking manufacturers for that same price?”

This suggests that private insurers may also seek similar pricing, potentially benefiting your non-Medicare patients in the future.

Managing Patient Expectations

The recent Medicare announcements represent two separate initiatives with distinct timelines and eligibility requirements.

The 2027 Inflation Reduction Act price negotiation reduces costs for patients with currently covered indications such as diabetes and cardiovascular disease.

The 2026 pilot program expands coverage to a specific subset of patients with obesity and qualifying comorbidities.

These are not interchangeable programs, and patients often conflate the two based on media coverage.

The Critical Question

When patients express excitement about “cheaper GLP-1s,” verify both coverage eligibility and the specific program that applies to their clinical situation.

Price reductions are only meaningful if the medication is covered for the patient’s indication under their Medicare Part D plan.

Examples:

  • A patient with obesity alone will not benefit from either program
  • A patient with obesity and hypertension may qualify for the 2026 pilot but not the 2027 price reduction (unless they also have a covered condition like diabetes)

Industry Response

The pharmaceutical industry has expressed concerns about government price setting. Alex Schriver, a spokesperson for PhRMA, stated in Reuters’ coverage that “whether it is the IRA or MFN, government price setting for medicines is the wrong policy for America.” However, these programs are moving forward regardless of industry opposition.

Conclusion

For your practice, the key is to cut through the headlines and help patients understand what these changes actually mean for their individual circumstances.

Not every patient will benefit, and those who do will benefit in different ways depending on their diagnoses, BMI, and which program they qualify for.

Accurate patient counseling requires:

  • Understanding which program applies
  • Confirming eligibility criteria
  • Verifying coverage with the patient’s specific Part D plan
Clear communication based on accurate understanding of both programs will help you manage patient expectations and avoid the frustration that comes from misunderstanding complex policy changes.

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