Members Login

Xeomin® Vs. Botox®

xeomin vs botox

Aesthetic medicine now uses botulinum toxin regularly in treating a variety of skin and muscle problems. Xeomin and Botox are two commonly used preparations, and in this article we will review the similarities and differences between these two preparations.


There are a number of similarities between Xeomin and Botox. These are listed below –

1. Both Xeomin and Botox consist of the same basic ingredient – Botulinum toxin A, a toxin that this produced by the Clostridium botulinum bacteria. This neurotoxin acts by blocking the neuromuscular junction and has an effect on the skin and muscles it is injected into.

2. Both Xeomin and Botox exert their effect in around 7 days after it has been injected, with the effects lasting up to 6 months. The overall effect that results from Xeomin and Botox are the same.

3. Both Xeomin and Botox are measured in the same units, making it easy for the treating physician to measure up the required dose.

4. The cost of Xeomin and Botox are comparable, making administration of either drug a choice that can lie with the physician or the patient.


There are only a few differences between Xeomin and Botox. These have been listed below –

1. The basic structure of Xeomin and Botox are different, even though the toxin is the same. Botox is encased within a protein structure, while Xeomin lacks this protein covering and is in fact the ‘naked’ botulinum toxin. This protein casing on Botox can cause immune reactions that can eventually block the actions on botulinum toxin when injected.  It is believed that this is an advantage that Xeomin bears over Botox as it results in no antibody formation with repeated injections of Xeomin.

2. Botox is stored in a freezer or at temperatures between 2 to 8°C. It therefore requires it to be transported in a freezer. On the other hand, Xeomin does not necessarily need to be stored in a freezer or refrigerator, making transporting the product a lot easier and even cheaper.

3.  is manufactured by Merz Pharma while Botox is manufactured by Allergan.

In most cases, Xeomin can be offered if patients develop antibodies to Botox.


Xeomin and Botox are very similar preparations of botulinum toxin A. Due to the lack of the protein casing and similar costs, preference to prescribe it depends on physician and patient choice.

For more information on the IAPAM’s Botox Training,


For more information on the IAPAM’s Aesthetic Medicine Symposium with Botox Training, visit

Submit a Comment

Your email address will not be published.