RN Botox® Injection Training: State Scope & Supervision Guide
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Last updated: September 2026
Jelly roll Botox® is one of the most requested and most misunderstood treatments in the lower face — and one of the easiest to get wrong. The target is a small band of muscle that sits a few millimetres below the lash line, so the difference between a subtly brighter eye and a patient who is unhappy with their smile can come down to two units and three millimetres. Getting it right starts with a working knowledge of the anatomy beneath each injection site.
Unlike the glabella or the crow’s feet, this area has no labeled dose to fall back on. What exists instead is a small, consistent body of published clinical work — including a dose-finding study that showed exactly where the risk curve turns upward. This guide pulls that evidence together: what the jelly roll actually is, where the needle goes, how many units is too many, which patients should be turned away, and what to do when a jelly roll appears because of a previous treatment.
Whether you are a clinic owner, an injector adding the lower lid to your repertoire, or a practitioner fielding the question from patients who saw it on social media, the goal is the same: know when the answer is yes, and be comfortable saying no.
“Jelly roll” is the informal term for a small roll or bulge of muscle that appears under the eye, most visibly when a patient smiles or squints hard. It is not caused by fat or fluid the way under-eye bags, festoons and puffiness are. It is the contraction of the pretarsal portion of the orbicularis oculi — the sphincter muscle that encircles the eye — bunching up over the tarsal plate.
That distinction is the whole treatment decision, so it is worth being precise about it:
A simple test: ask the patient to relax completely, then to smile widely. If the roll only appears with the smile, it is muscular and is a candidate for toxin. If it is there at rest, you are looking at volume or laxity, and the wider question of what Botox® can and cannot do under the eyes applies instead.
Yes, and patients should hear it during consent. BOTOX® Cosmetic is FDA-approved for glabellar (frown) lines, lateral canthal lines (crow’s feet), forehead lines and platysma bands. The lower eyelid is not on that list. Injecting the pretarsal orbicularis to soften a jelly roll or widen the eye is an established off-label technique — supported by published clinical studies, but not by labeled dosing.
Practically, that means two things. There is no manufacturer-sanctioned unit range to hide behind, so your dose has to be defensible from the literature. And because there is no labeled indication, documentation of the discussion, the assessment and the dose matters more here than almost anywhere else on the face.
The technique described in the published work is narrow and specific. The injection is placed in the midpupillary line, approximately 3 mm below the ciliary (lash) margin, delivered just subdermally into the pretarsal orbicularis. Small volume, superficial plane, one point per side.
Three things keep that injection safe. Staying superficial keeps the toxin in the pretarsal muscle rather than letting it reach the lower lid retractors or the inferior oblique. Staying on the midpupillary point avoids drifting medially toward the lacrimal drainage or laterally into the zone already treated for crow’s feet. And keeping the volume small limits how far the toxin can spread from where you put it — in this area, diffusion is the complication.
This is the part of the conversation that most often goes wrong, because the instinct — if a little works, more will work better — is exactly backwards here. Flynn and the Carruthers published two studies that map the dose-response curve in the lower lid, and the second one was designed specifically to ask whether going above 2 units is worth it.
It is not. Higher doses did produce slightly more eye-widening, but in the 8-unit groups every single patient reported bothersome side effects — lower eyelid swelling and incomplete sphincter function among them. The authors’ recommendation was to stay at 2 to 4 units. Think of the pretarsal muscle as the drawstring on a bag: loosen it a little and the gather smooths out, loosen it too far and the whole thing sags open.
| Protocol | Eye opening at rest | At full smile | Side effects |
|---|---|---|---|
| 2 U lower lid only | +0.5 mm | +1.3 mm | Minimal; only 40% showed any widening |
| 2 U lower lid + crow’s feet | +1.8 mm | +2.9 mm | Minimal; 86% showed widening |
| 4 U lower lid only | +1.8 mm | +2.6 mm | Dose-related, generally tolerated |
| 4 U lower lid + crow’s feet | +2.2 mm | +4.5 mm | Dose-related; upper end of the safe range |
| 8 U lower lid only | +2.2 mm | +2.9 mm | All 8 patients reported bothersome effects |
| 8 U lower lid + crow’s feet | +1.5 mm | +4.0 mm | All 8 patients reported bothersome effects |
Read the middle rows carefully, because they contain the useful clinical lesson: 2 units in the lid plus a standard crow’s feet treatment outperformed 8 units in the lid alone at rest. The synergy comes from treating the muscle as a unit rather than from loading one point — the same logic that drives how the lateral orbital area is dosed for crow’s feet. At the highest doses the benefit plateaus while the side effects keep climbing.
Some patients want a rounder, more open-looking eye rather than a smoother lid. Relaxing the pretarsal muscle does widen the palpebral aperture — it has been measured — but the numbers are small, and managing that expectation is most of the consultation.
Average increase in eye opening at full smile
At 2 units in the lid alone, the average gain was half a millimetre at rest, and only 40% of patients showed any measurable increase at all. Adding the crow’s feet treatment raised that to 86% of patients and an average of 1.8 mm at rest. The published work also noted the effect was more notable in the Asian eye, where a rounder aperture is more often the aesthetic goal.
The demand side has changed since this technique first appeared. Eye-widening was once described as a mainly East Asian request; it is now a mainstream consumer search in North America and the UK, driven by social media. That does not make the millimetres bigger — it means more patients will arrive with expectations set by a filtered video, and the honest version of this number is your best tool.
This is where the treatment is won or lost. The lower lid tolerates very little, and the margin for error narrows with age as the skin thins and the lid loses support. A tiny overdose in the wrong patient shows up as extra sclera (the white of the eye) or a smile that no longer looks like theirs.
Before treating, assess the lid rather than eyeballing the patient’s age:
A structured assessment habit is what makes this consistent from patient to patient — the same discipline covered in our facial analysis checklist for Botox® trainees. When two or more of the findings above are present, the safe answer is to decline the lower lid and offer an alternative.
Almost every problem in this area is dose-related, selection-related, or both. Knowing the specific failure modes is what lets you set expectations honestly and recognise a problem early:
Worth noting for consent: the lid complication patients ask about most is not the jelly roll itself but the eyelid dropping. That is a different mechanism entirely — see droopy eyelid after Botox® (ptosis) for how upper lid ptosis arises and how it is managed.
A question injectors field regularly: a patient who never had a jelly roll now has one, after a crow’s feet treatment. It is a balance problem, not a new condition. When the lateral orbicularis is relaxed and the pretarsal band below the lash line is left at full strength, the untreated portion can look and behave more prominently on smiling. Relative, not absolute, change.
The fix is usually small: a very low pretarsal dose at the next visit to even out the sphincter, or a change in crow’s feet placement at the following treatment. It is also a good argument for planning the periocular area as one unit from the start rather than treating each line in isolation.
Onset is typically three to seven days, with periocular toxin effects generally lasting around three to four months. Because the doses here are so small, some patients notice the softening fading before their glabella or crow’s feet results do. Say that at consultation — a patient who was told to expect four months and sees movement return at ten weeks will read a normal result as a failure.
Not all under-eye lines respond to toxin, and it is worth being blunt with patients about which of theirs will. Some lines are simply part of the eye’s natural structure rather than creases that can be erased. Others come from the lower orbicularis at rest, and a very small dose can soften those. But lines that appear mainly on smiling, or that originate in the cheek muscles, will not improve from a lower lid injection.
And when the underlying problem is lost volume or thinning skin as the face ages, toxin is the wrong tool entirely — volume replacement or a filler approach will serve the patient better, and offering it is often what earns their trust. The judgement call is the same one that runs through planning the full face as one balanced treatment: treat the cause you actually found, not the one the patient named.
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No. BOTOX® Cosmetic is FDA-approved for glabellar (frown) lines, lateral canthal lines (crow’s feet), forehead lines and platysma bands. Injecting the pretarsal orbicularis oculi of the lower eyelid to soften a jelly roll or widen the eye is an off-label use. Off-label does not mean improper, but it does mean the technique rests on published clinical experience rather than on labeled dosing, and patients should be told that during consent.
The published range is 2 to 4 units per lower eyelid. A dose-finding study by Flynn and colleagues compared 4 units with 8 units and found that every one of the eight patients in the 8-unit groups reported bothersome side effects, including lower eyelid swelling and incomplete eye closure. The authors recommended staying at 2 to 4 units. More toxin buys a fraction of a millimetre of extra eye opening and a much higher chance of an unhappy patient.
In the published technique the injection sits in the midpupillary line, approximately 3 millimetres below the ciliary (lash) margin, placed just subdermally into the pretarsal portion of the orbicularis oculi. It is a superficial, small-volume injection. Staying superficial and staying on that single midpupillary point is what keeps the toxin in the pretarsal muscle instead of diffusing toward the lower lid retractors or the inferior oblique.
Measurably, yes, but by very little. With 2 units in the lower lid alone, the palpebral aperture increased by an average of 0.5 mm at rest and 1.3 mm at full smile, and only 40 percent of patients showed any increase. When the lower lid was treated together with the crow’s feet, the average increase rose to 1.8 mm at rest and 2.9 mm at full smile, and 86 percent of patients showed an increase. The effect was described as more notable in the Asian eye. Patients expecting a dramatic change should be redirected.
Yes. The recognised problems are lower eyelid swelling, excess scleral show, an asymmetric or pinched smile, watering or dry, gritty eyes from a weakened lacrimal pump, and — in a patient with true fat herniation — a bag that looks worse rather than better. A 2025 study of intradermal toxin for mild tear troughs reported one case of pseudo-eyelid bags among 42 patients. Almost all of these are dose- and selection-related, not bad luck.
It happens. When the lateral orbicularis is relaxed for crow’s feet and the pretarsal portion below the lash line is left at full strength, the untreated muscle can look and act more prominent on smiling, so a roll appears where there was none before. It is a balance problem rather than a new condition, and it is usually managed at the next visit with a very small pretarsal dose or by adjusting the crow’s feet placement.
Onset is typically three to seven days, and periocular toxin effects generally last around three to four months. Because the doses used in the lower lid are so small, some patients notice the softening fading sooner than their frown line or crow’s feet results. That shorter tail is worth mentioning at consultation so a patient does not read a normal return of movement as a failed treatment.
Jelly roll Botox® works, in the right patient, at the right dose, in the right plane. Two to four units, 3 mm below the lash margin, in the midpupillary line, in a patient whose lid snaps back and whose roll disappears at rest. Outside those conditions the treatment stops being subtle and starts being memorable for the wrong reasons — which is why the most valuable skill here is the confidence to decline and offer something better.
If you are adding the lower lid to your practice, the safest way to learn it is on live models with an instructor watching your plane and your volume. IAPAM’s hands-on Botox® training is taught by board-certified dermatologists in a clinical setting in Scottsdale, Arizona, and covers the periocular area as a planned unit rather than a set of isolated lines.
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Disclaimer: This guide is for informational and educational purposes only and does not constitute medical advice. Treatment plans, injection techniques, and dosing must be tailored to each patient by a qualified, licensed provider. Always follow product labeling, your scope of practice, and your state medical and nursing board regulations.
Sometimes, people want more rounded or open-looking eyes. This is especially popular in some East Asian countries, where a round eye is considered attractive. Injecting Botox® just under the pupil can relax part of the lower eyelid muscle and create a subtle widening effect.
However, in Western cultures, most people prefer an almond eye shape, and this treatment is less commonly requested.
“Jelly Roll” is a term used in aesthetic medicine to describe a small roll or bulge of muscle that appears under the eyes, especially when smiling or squinting. It is not caused by fat or fluid (like under-eye bags or puffiness), but rather by the contraction of the orbicularis oculi muscle, which encircles the eye.
Not everyone is a good candidate for under-eye Botox®. The area is delicate, and the risk of problems is far greater with age, as the skin gets thinner and loses support. The margin for error is smaller in older patients, and even a tiny overdose can result in unwanted side effects like extra sclera (white part of the eye) showing or a smile that looks less natural.
Injecting Botox® under the eye can be helpful for certain people, particularly younger patients with muscle-related lines or a clear jelly roll. However, for many individuals, this treatment is not recommended because of the risks and potential for unnatural or displeasing results. It is best reserved for carefully chosen cases and always performed by experienced aesthetic practitioners who understand the underlying anatomy.
If you are considering Botox® under the eyes or have concerns about under-eye lines or bulges, consult a knowledgeable provider for a personalized evaluation and discussion of all your options—including safer and sometimes more effective alternatives.
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